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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
31.82
Human Site:
T660
Identified Species:
46.67
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T660
I
E
N
G
H
I
F
T
V
N
D
Q
F
T
S
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
T649
I
E
N
G
H
I
F
T
V
N
D
Q
F
T
S
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
T638
I
E
N
G
H
I
F
T
V
N
D
Q
F
T
S
Dog
Lupus familis
XP_534586
746
86477
T638
I
E
N
G
H
I
F
T
V
N
D
Q
F
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T660
I
E
S
G
H
I
F
T
V
N
D
Q
F
T
S
Rat
Rattus norvegicus
Q9JJ31
780
90872
A678
D
F
S
L
I
K
N
A
K
V
Q
K
R
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
L543
N
D
Q
F
T
S
K
L
H
R
V
K
I
Q
T
Chicken
Gallus gallus
XP_422620
768
88957
T660
I
E
N
G
H
I
F
T
V
N
D
Q
F
T
S
Frog
Xenopus laevis
Q6DE95
768
88933
T660
I
E
S
G
H
M
F
T
V
N
D
Q
F
T
S
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
T658
I
E
S
G
H
V
F
T
V
N
D
Q
F
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
D672
S
T
V
E
L
F
L
D
Y
K
N
K
K
R
R
Honey Bee
Apis mellifera
XP_625079
767
89385
C660
I
E
P
S
H
Y
F
C
V
N
D
S
F
T
S
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
F669
A
I
D
M
S
D
E
F
A
V
N
D
N
F
Q
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
V576
E
N
P
H
M
F
S
V
N
D
A
F
T
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N638
Q
N
D
A
F
E
F
N
S
K
F
T
D
R
M
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
F638
K
F
S
V
N
Y
F
F
S
S
P
N
R
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
0
100
86.6
86.6
N.A.
0
66.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
100
100
100
N.A.
13.3
66.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
7
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
7
13
0
0
7
0
7
0
7
57
7
7
0
0
% D
% Glu:
7
57
0
7
0
7
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
7
7
13
69
13
0
0
7
7
57
7
0
% F
% Gly:
0
0
0
50
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
0
0
7
57
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
57
7
0
0
7
38
0
0
0
0
0
0
7
0
0
% I
% Lys:
7
0
0
0
0
7
7
0
7
13
0
19
7
7
13
% K
% Leu:
0
0
0
7
7
0
7
7
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
7
7
0
0
0
0
0
0
0
0
7
% M
% Asn:
7
13
32
0
7
0
7
7
7
57
13
7
7
0
0
% N
% Pro:
0
0
13
0
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
7
0
7
0
0
0
0
0
0
0
7
50
0
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
13
13
7
% R
% Ser:
7
0
32
7
7
7
7
0
13
7
0
7
0
7
57
% S
% Thr:
0
7
0
0
7
0
0
50
0
0
0
7
7
57
7
% T
% Val:
0
0
7
7
0
7
0
7
57
13
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
13
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _